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Autism spectrum disorder children have feeding problems because most of them are selective eaters. Therefore, it is difficult to apply a Ketogenic Diet to children with Autism spectrum disorder. There are also some side effects of the long-term implementation of a Ketogenic Diet in children. The main side effects of Ketogenic Diet treatment in children are constipation, vomiting, lack of energy, and hunger. Late-onset adverse effects include hyperuricemia, hyperlipidemia, and kidney stones. One serious side effect of a Ketogenic Diet in children is the suppression of physical development. Long-term Ketogenic Diet administration decreased growth, as indicated by height z-scores but growth, as indicated by weight z-scores, did not change. A Ketogenic Diet may cause height deceleration. However, these side effects do not occur often, and a Ketogenic Diet has been widely used in children with refractory epilepsy. In summary, although studies with larger samples of Autism spectrum disorder patients are lacking, Ketogenic Diet is a safe and effective treatment in people with Autism spectrum disorder. | Autism spectrum disorder children have feeding problems because most of them are selective eaters. Therefore, it is difficult to apply a Ketogenic Diet to children with Autism spectrum disorder. There are also some side effects of the long-term implementation of a Ketogenic Diet in children. The main side effects of Ketogenic Diet treatment in children are constipation, vomiting, lack of energy, and hunger. Late-onset adverse effects include hyperuricemia, hyperlipidemia, and kidney stones. One serious side effect of a Ketogenic Diet in children is the suppression of physical development. Long-term Ketogenic Diet administration decreased growth, as indicated by height z-scores but growth, as indicated by weight z-scores, did not change. A Ketogenic Diet may cause height deceleration. However, these side effects do not occur often, and a Ketogenic Diet has been widely used in children with refractory epilepsy. In summary, although studies with larger samples of Autism spectrum disorder patients are lacking, Ketogenic Diet is a safe and effective treatment in people with Autism spectrum disorder. | ||
Autism spectrum disorder is a neurodevelopmental disease, and timely and effective treatment help improve the prognosis. There is no effective treatment for Autism spectrum disorder children. Many treatments are used for Autism spectrum disorder, but there are no curative treatments for all of the core features of Autism spectrum disorder. A Ketogenic Diet may improve social behavior in Autism spectrum disorder via normalizing GABA, improving mitochondrial function, ameliorating inflammatory activity and oxidative stress in the brain, inhibiting the mTOR signaling pathway, and modulating the gut microbiota. However, the effects of Ketogenic Diet vary widely between Autism spectrum disorder patients, and the underlying mechanisms are not known. Autism spectrum disorder children may also reject Ketogenic Diet food because of their selective eating habits, which complicates the introduction of a Ketogenic Diet to Autism spectrum disorder patients. Some studies showed that Autism spectrum disorder children have nutrient deficiencies, including vitamin D and folic acid. Long-term treatment of a Ketogenic Diet likely aggravates the nutritional deficiency. The benefits of a long-term Ketogenic Diet treatment in Autism spectrum disorder children are not known. Therefore, more studies with larger samples and long-term Ketogenic Diet treatment are needed to demonstrate the beneficial effects of a Ketogenic Diet and its side effects in children with Autism spectrum disorder. | |||